P&S Market Research

スキンケアデバイスの世界市場規模・シェア・開発・成長・需要予測(2013~2023年):商品別(光・LED治療・フォトトリートメント、脂肪吸引、電気手術、レーザー治療、クライオセラピー、マイクロダーマブレージョン、皮膚鏡、生検装置、画像誘導システム)・用途別(セルライト除去、疾患診断・治療、脱毛、スキンタイトニング・体形矯正、若返り術)・地域別(米国、カナダ、ドイツ、イギリス、フランス、イタリア、スペイン、日本、中国、インド、オーストラリア、ブラジル、メキシコ、南アフリカ、イスラエル、サウジアラビア、アラブ首長国連邦)

2018年3月2日 // 0 Comments

The growth in the skincare devices market will be led by increasing cases of skin cancer and skin related disorders, technological advancements in skincare devices, increase in disposable income, rising demand for aesthetic procedures, and growing geriatric population.
Insights on market segments

The products used in the skincare devices market have been categorized as skin treatment devices and skin diagnostic devices. The market for the latter is expected to witness the fastest growth at a CAGR of 11.9% during the forecast period. This rising demand for skincare diagnostic devices can be attributed to the increasing prevalence of skin diseases, especially skin cancer, the diagnosis of which requires the use of these devices.

Skin treatment devices held the largest share in the skincare devices market in 2017. These devices include light/LED therapy and photorejuvenation, liposuction, electrosurgical, laser based, cryotherapy, microdermabrasion, and others. Light/LED therapy and photorejuvenation devices are estimated to capture the largest share of the skin treatment devices market in 2017. This is due to the worldwide growth in aging population, and increasing popularity of these devices as a way to fight acne, and many signs of aging. Laser based devices are expected to witness the fastest growth in demand, at a CAGR of 11.9% during the forecast period.

Cellulite reduction is the largest application category in the skincare devices market, which can be attributed to the high prevalence (80%–90%) of cellulite in post-pubertal female patients of all races and rising ageing population. On the other hand, the skin tightening and body contouring application category is expected to witness the fastest growth in demand for skincare devices, during the forecast period. The growth for skin tightening and body contouring services is driven by the increasing prevalence of obesity and growing number of people undergoing liposuction, who in turn require skin tightening for avoiding the problem of loose skin.

Asia-Pacific (APAC) is the fastest growing market for skincare devices

The skincare devices are expected to witness the fastest growth in demand in APAC, at a CAGR of 12.5% during the forecast period, owing to a large population, higher prevalence of skin diseases and obesity, and aging population in the region.

According to the United Nations Economic and Social Commission for Asia and the Pacific (UNESCAP), people aged 65 years and above constituted approximately 11.4% of the population in 2013, and the count is estimated to increase by approximately 20% by 2050. The geriatric population is at a greater risk of skin cancer. According to the Skin Cancer Foundation, the majority of people diagnosed with melanoma are white men, above 55 years of age. Also, the elderly people generally face problems such as wrinkles, cellulite, loose skin, obesity and therefore, fueling the growth of the APAC skincare devices market.

Key Players Look to Technological Advancements for Market Expansion

The key players in the skincare devices industry are developing and launching new skincare devices that are equipped with latest technology, to gain a larger market share. For instance, in May 2017, Cutera Inc. launched truSculpt 3D, a new technology in body sculpting that offers up to 24% fat reduction in a single operation.

Some of the other key players operating in the skincare devices market include Allergan plc, Merz Pharma GmbH & Co. KGaA, Syneron Medical Ltd., Michelson Diagnostic Ltd., Lumenis Ltd., PhotoMedex Inc., Alma Lasers Ltd., Hologic Inc., Panasonic Corporation, Valeant Pharmaceuticals International Inc., and Beijing Toplaser Technology Co Ltd.

オッセオインテグレーションインプラントの世界市場規模・シェア・開発・成長・需要予測(2013~2023年):商品別(骨支持型義肢(脊椎固定、聴覚、上腕用義肢、下肢用義肢)歯科用インプラント(クラウン、インプラント、アバットメント))・素材別(メタリック、セラミクス、高分子)・エンドユーザー別(病院、歯科クリニック、ASC)・地域別(米国、カナダ、ドイツ、フランス、イギリス、日本、オーストラリア、インド、中国)

2018年3月2日 // 0 Comments

The growth in the market will be led by the increasing prevalence of spinal cord injuries, rise in the number of dental implant surgeries, reimbursement support by government and other organizations, rising number of trauma incidents, increasing hearing loss cases in the geriatric population, and spur in the funding for osseointegration research.
Insights on market segments

In terms of product type, the osseointegration implants market has been categorized as dental implants and bone-anchored prostheses. Dental implants are expected to witness a faster growth in demand, with a CAGR of 4.6% during the forecast period, owing to increasing prevalence of dental disorders and rising awareness about dental implants as a tooth-loss solution.

By material type, ceramic biomaterials are expected to project the fastest growth in demand with a CAGR of 4.2% during the forecast period. The growth of ceramic biomaterials is attributed to their tribological properties, biocompatibility, and aesthetic appearance. On the basis of end user, the osseointegration implants industry is categorized into hospitals, ambulatory surgical clinics (ASCs), and dental clinics. Due to the increasing number of dental implant procedures worldwide, the demand of osseointegration implants in dental clinics is expected to advance at a CAGR of 3.4% during the forecast period.

Asia-Pacific to exhibit fastest growth, with 4.8% CAGR during the forecast period

The osseointegration implants market in Asia-Pacific is expected to witness a significant growth during the forecast period. This growth is attributed to factors such as increasing development and research activities, rising disposable income that enables people to select appropriate treatment options, and access to modern healthcare facilities.

Technologically advanced countries such as Australia, are increasingly focusing on the development of implantable procedures for upper and lower limb amputees, enabling the manufacturers of osseointegration implants in bone-prostheses to grow significantly in this region. Moreover, the increasing dental tourism in countries such as India and Thailand have facilitated the growth of the osseointegration market for dental implants.

Major players launching innovative products to gain a larger market share

Globally, the key providers in the osseointegration implants industry are launching new products to gain a larger market share. For instance, in June 2017, DePuy Synthes Companies announced the launch of the VIPER and EXPEDIUM Fenestrated Screw Systems in the U.S. The system along with CONFIDENCE High Viscosity Spinal Cement would restore the integrity of the spinal column in patients with advanced stage spinal tumors.

Similarly, in January 2017, Integrum AB launched the new OPRA Implant System Platform G, which is to be used for transfemoral patients. The new platform is CE labeled and approved by the USFDA, which improves the mechanical performance of the system, simplifies the surgical procedure, and enhances osseointegration.

Some of the other key players operating in the osseointegration implants market include Zimmer Biomet Holdings Inc., Dentsply Sirona Inc., Danaher Corporation, The Straumann Group, Henry Schein Inc., Stryker Corporation, NuVasive, Inc., William Demant Holding A/S, Cochlear Ltd., and Medtronic plc.

ヘルスケアコグニティブコンピューティングの世界市場規模・シェア・開発・成長・需要予測(2014~2024年):技術別(自然言語処理(NLP)、機械学習、自動推論、情報検索)・展開モデル別(オンクラウド、オンプレミス)・エンドユーザー別(ヘルスケアプロバイダー、医薬品企業、医療機器企業、ヘルスケアペイヤー)、・地域別(米国、カナダ、イギリス、ドイツ、フランス、中国、日本、インド、ブラジル)

2018年3月2日 // 0 Comments

The growth in the healthcare cognitive computing market size will be led by increasing burden of chronic diseases, technological advancements in the healthcare industry encouraging the use of cognitive computing in healthcare, and rising adoption of third computing platforms.
Insights on market segments

The technologies used in the healthcare cognitive computing market have been categorized as natural language processing (NLP), machine learning, automated reasoning, and information retrieval, where NLP is expected to witness the fastest growth in demand, and is likely to garner a CAGR of 34.9% during the forecast period. This rising demand for the NLP technology can be attributed to its comprehensive evaluation process, which facilitates management of patient feedback and enables clinical staff to make informed decisions and respond to problems in real time. For instance, the U.S. based Intermountain Hospital uses the NLP technology to identify information associated with cardiac patients, cancer patients, and venous thromboembolism patients.

Cloud and on-premise are the two major types of deployment models used in the healthcare cognitive computing market. Globally, the cloud computing deployment model is estimated to acquire a larger market share, standing at 71.0% in 2017. This growth in the cloud computing deployment model is mainly attributed to its increasing use in the development of healthcare applications, such as electronic health records (EHRs), which are affordable and easily accessible to the healthcare providers to store and access data remotely and provide the necessary care without any delay.

Although cognitive computing is being increasingly used in healthcare by various healthcare professionals, it is the healthcare providers category that is expected to witness the fastest growth, as the end-user base, in the healthcare cognitive computing market during the forecast period. Healthcare providers have been estimated to lead the global market, occupying a 44.5% share in 2017. This growth in the demand for healthcare cognitive computing solutions by healthcare providers can be attributed to the increased usage of cognitive platforms by the providers for the detection and treatment of rare diseases. For instance, in October 2016, Rhön-Klinikum AG, a private hospital group in Germany, teamed up with IBM Corporation on a 12-month pilot project to help detect rare diseases and find their cure using the IBM’s Watson platform.

Asia-Pacific (APAC) is the fastest growing market for healthcare cognitive computing solutions

The APAC healthcare cognitive computing industry is expected to witness the fastest growth in demand, at a CAGR of 41.6%, during the forecast period, owing to rising geriatric population, increasing healthcare expenditure, growing public and private investments in the healthcare sector to cater to unmet medical needs, and burgeoning pharmaceutical industry in the region.

According to the United Nations Economic and Social Commission for Asia and the Pacific (UNESCAP), people aged 65 years and above constituted approximately 11.4% of the population in 2013, and the count is estimated to increase by approximately 20% by 2050. Since the elderly generally need help in meeting their medication needs, including keeping track of their visits to the doctor, medication timings, exercise reminders, and dietary recommendations, there is ample scope for the healthcare cognitive computing market to flourish in the region.

Companies in the healthcare cognitive computing market are also increasingly getting involved in research and development to provide better healthcare solutions. For instance, in August 2016, IBM Watson aided in the detection of a rare form of leukemia in a patient in Japan. The cloud-based, AI-powered supercomputer of IBM is capable of cross-referencing and analyzing data from millions of oncology papers from research institutes all over the world.

Development of advanced healthcare computing solutions by key players, to gain a larger share

Globally, key players in the healthcare cognitive computing industry are developing advanced computing solutions for healthcare, to gain a larger market share. For instance, in November 2017, Nuance Communications Inc. unveiled Nuance AI Marketplace for Diagnostic Imaging at the Radiological Society of North America (RSNA) conference in Chicago. It is the first open platform for developers, data scientists, and radiologists to accelerate the development, deployment, and adoption of AI for medical imaging.

Some of the other key players operating in the healthcare cognitive computing market include IBM Corporation, Microsoft Corporation, Enterra Solutions, LLC, Intel Corporation, Alphabet Inc., Hewlett Packard Enterprise (HPE), CognitiveScale, Healthcare X.0 GmbH, and MedWhat.com Inc.

老視(老眼)治療薬のパイプライン分析

2018年3月1日 // 0 Comments

The study analyzed that the presbyopia therapeutics pipeline comprises nine drug candidates in different stages of development. Presbyopia is an age-related eye condition that causes visual impairment gradually. The disease has been described as “an irreversible optical failure, an unexplained evolutionary blunder that comes as a psychologic shock”. Though not incapacitating if corrected, presbyopia without optical correction results in an inability to perform once-effortless near tasks at a customary working distance without experiencing visual symptoms. The disease can result from the gradual decrease in the amplitude of accommodation.
Insights on pipeline segments

Various pharmaceutical companies such as Novartis AG, Allergan Plc., Janssen Global Services LLC, and Acucela Inc. are engaged in the development drug candidates for the treatment of presbyopia.

Positive clinical results of presbyopia drug candidates

Various pharmaceutical companies are developing drug candidates for the treatment of presbyopia, which have shown positive results in different stages of development. For instance, UNR844 showed a statistically significant difference to placebo in distant corrected near vision at all time points measured (from day 8) in the Phase I/II, placebo-controlled, proof-of-concept study carried out in 50 patients daily for 90 days with topical UNR844 and in 25 patients with placebo. At day 90, 82% of participants treated with UNR844 had 20/40 near vision (or 0.30 LogMAR) versus 48% in the placebo group. Near vision of 20/40 allows the majority of near vision tasks in most people.

Novel delivery systems and patented technologies for Presbyopia

Various pharmaceutical companies are involved in manufacturing drugs for the treatment of presbyopia. In January 2017, Alcon, the eye care division of Novartis AG, launched AcrySof IQ PanOptix Toric intraocular lens for presbyopia. The launch of the AcrySof IQ PanOptix Toric intraocular lens is a significant achievement in presbyopia treatment. Most of the drug candidates have received or have filed for patent covering a novel mechanism for the treatment of presbyopia.

Some of the key players developing Novartis AG, Allergan Plc, and ORASIS Pharmaceuticals Ltd.

ニューロフィブロマトーシス(神経線維腫症)治療薬のパイプライン分析

2018年3月1日 // 0 Comments

The study analyzed that the Neurofibromatosis therapeutics pipeline comprises of approximately 25 therapeutic candidates in different stages of development.
Insights on pipeline segments

Majority of the pipeline drug candidates are being developed to be administered by oral route. Celldex Therapeutics Inc. and Merck Co. Inc. are in the process of developing a monoclonal antibody drug candidate, CDX0158, and Pembrolizumab respectively for the treatment of NF. Lixte Biotechnology Holdings Inc. is in the process of developing two drug candidates, in the Pre-Clinical stage of development for the treatment of neurofibromatosis (NF). In September 2016, the USFDA granted Orphan Drug Designation to BXCL101, a drug candidate of BioXcel Therapeutics Inc. for the treatment of NF type 2.

Unmet medical needs driving the neurofibromatosis therapeutics pipeline

Since there is no treatment available for NF, the growing medical needs of the people suffering from the disease are driving its therapeutics pipeline growth. High rate of recurrence/progression of the disease and poor long-term benefit of surgery can be viewed as a limitation of this treatment option.

Positive clinical trial results propelling the growth of the pipeline therapeutics of the Neurofibromatosis

The drugs being developed by the different pharmaceutical companies demonstrated positive clinical trial results which in-turn increasing their further development. For instance, In June 2014, Array BioPharma Inc. announced positive results of Phase I/II, combination of binimetinib and LEE011. Selumetinib being developed by the AstraZeneca plc. And it met primary endpoint as confirmed partial responses (tumor volume decreases from baseline of ≥20%) in 17 of the 24 children (71%) in Phase I study.

Some of the key players developing drugs for the treatment of neurofibromatosis include Novartis AG, AstraZeneca Plc, Pfizer Inc., GlaxoSmithKline plc, Merck & Co. Inc, BioXcel Therapeutics, Inc.

便秘治療薬のパイプライン分析

2018年3月1日 // 0 Comments

The study analyzed that the constipation therapeutics pipeline comprises approximately 18 drug candidates in different stages of development. Most of the drugs in pipeline for the treatment of constipation are in late stage of development. Constipation is a common functional gastrointestinal (GI) disorder that is most prevalent in the elderly and female population. According to the journal Clinical Interventions in Aging, published in 2015, the prevalence of the disease is around 20% in the world population, varying between 2% and 27% in different countries. The economic impact of chronic constipation is significant in the U.S., with around 100,000 constipation-related hospitalizations annually.
Insights on pipeline segments
Pharmaceutical companies are developing various drug candidates for the treatment of constipation in different stages of development including Filed, Phase III, Phase II, Phase I, and Pre-clinical. Albireo Pharma Inc. is in the process of developing a drug candidate, which is in the Filed stage of development, for treating constipation. There are small molecules as well as peptide type drug candidates in development for the treatment of constipation. A majority of the constipation therapeutics pipeline drugs are being developed as an oral dosage form.

Increasing prevalence of GI disorders boosting the growth of constipation pipeline

There has been considerable increase in the prevalence of GI disorders, such as non-alcoholic fatty liver disease, diabetes, pancreatitis, and acidity, in people. These problems have a huge impact on the digestion process, which, in turn, causes constipation. It has also been observed that synthetic foods too cause indigestion in people, which results in constipation. Thus, unhealthy dietary behavior too increases the chances of occurrence of constipation. Thus, increasing prevalence of GI disorders contributes as one of the key drivers for the development of drugs to treat constipation.

Technological advancements for the development of drug candidates to treat constipation

With advances in technology, many pharmaceutical companies are leveraging new and improved technologies for the development of drug candidates to treat constipation. These technologies are helpful in the development of drugs as either combination therapies or single-agent therapies. They also allow development of specific targeted therapies with better drug delivery. For instance, Ardelyx Inc. has developed a unique platform that enables to discover targets in the GI tract, which control health and disease processes to optimize drug candidates and to understand their mechanisms of action.

Some of the players involved in the development of drug candidates for the treatment of constipation are Nordic Life Science Pipeline Inc., Enterin Inc., and Yuhan Corporation Ltd.

mTOR阻害薬のパイプライン分析

2018年3月1日 // 0 Comments

The mechanistic/mammalian target of rapamycin (mTOR) is a serine threonine protein kinase, that belongs to the phosphatidylinositol-3-kinase-related kinase family. Molecules in this family have more than 2,500 amino acids, and they harbor a kinase domain at their C-terminals. It has been observed that the increasing prevalence of cancer along with its high healthcare cost, globally, has been driving the growth of mTOR inhibitors pipeline. For instance, the number of people living beyond cancer diagnosis reached around 14.5 million in 2014 and is expected to increase to 19 million, by 2024. In 2010, approximately $125 million was spent on cancer care in the U.S., and it is expected to reach $156 million, by 2020.
Other factors strengthening the mTOR inhibitors pipeline include smoking, obesity unhygienic food, and allergy. The study analyzed that mTOR inhibitors therapeutics pipeline comprises approximately 30 drug candidates in different stages of development.

Insights on pipeline segments

According to the research findings, most of the drug candidates that act as mTOR inhibitors are being developed as small molecules, further supported by the fact that small molecules have several advantages such as it can be manufactured with production rate higher than any other molecule types.

Positive Clinical Results of mTOR Inhibitors Therapeutics Candidates

The positive clinical results of mTOR inhibitors drug candidates is a key factor driving the pipeline growth. For instance, F. Hoffman-La-Roche AG has developed a drug candidate, ipatasertib, that acts as mTOR inhibitors. The Phase II clinical results (Study ID: NCT02162719) of the drug candidate were published in the Lancet Oncology journal. It has been observed that progression-free survival was longer in patients who received ipatasertib as compared in those who received placebo.

Technological Advancements for mTOR Inhibitors Therapeutics Drug Development

Most of the companies are developing innovative technologies for the synthesis or production of mTOR inhibitors. For instance, PHusis Therapeutics Inc. is using its computational modeling platform namely, PHuDock, that identify inhibitors of proteins which promotes the growth of cancer cells. Using PHuDock, X-ray structural information and surface plasmon resonance spectroscopic measurements of selected drug-like molecules, PHusis is rapidly and efficiently identifying agents involving toxicity studies, that selectively inhibit the activity of a number of these cancers driving proteins. PHuDock is applied to lead identification and optimization, as well as to predict the compounds off-target properties and toxicity, therefore delivering novel and highly effective agents with low toxicity.

These technologically advanced platforms enable the players in the pipeline to develop effective new therapies rapidly, that are cost effective and potentially have lower risk of toxicity, and relative to traditional approaches. Thus, these technological advancements act as a key driver for the pipeline growth.

Some of the key players involved in the development of mTOR inhibitors therapeutics include F. Hoffman-La-Roche AG, Pfizer Inc., and resTORbio Inc.